The most typical Uncomfortable side effects of codeine are stated down below. Convey to your Health care service provider if you have any of these Unwanted side effects that trouble you.
Codeine sulfate is undoubtedly an opioid analgesic indicated for the reduction of mild to moderately serious pain wherever the use of an opioid analgesic is acceptable.
Keep in mind, keep this and all other medicines out of your arrive at of kids, in no way share your medicines with Other people, and use promethazine just for the sign prescribed.
Promethazine is not really for use in treating indications of bronchial asthma, pneumonia, or other decrease respiratory tract infections.
Stay away from excessive Sunlight publicity or artificial ultraviolet light-weight whilst acquiring promethazine; request healthcare suggestions if pores and skin redness or pores and skin eruptions establish. Dress in Solar-protective clothing and take into consideration SPF30+ Sunshine protection when outside the house if publicity to daylight is unavoidable.
Due to the possibility of potentially deadly respiratory melancholy, promethazine hydrochloride really should not be Utilized in young children young than two several years of age. The drug must be employed cautiously and at the lowest powerful dosage in older kids (See Cautions: Pediatric Precautions.)
Codeine could be abused inside of a method just like other opioid agonists, lawful or illicit. This should be viewed as when prescribing or dispensing codeine sulfate in situations wherever the medical doctor website or pharmacist is worried about an increased possibility of click here misuse, abuse, or diversion.
Promethazine also has become demonstrated to obtain immunosuppressive exercise in animals. Despite the fact that some knowledge prompt the drug may possibly lessen the range and function of fetal T-cells when administered chronically all through pregnancy, other details reveal that the drug would not have an affect on the quantity of fetal T- or B-cells; more studies within the possible outcomes of promethazine on fetal immunocompetence are desired.
Breathing Problems. Codeine may perhaps lead to sluggish or shallow respiratory, particularly when you've got respiratory difficulties from another issue or acquire other medicines that will sluggish your breathing.
Never flush down a bathroom or pour down a drain Unless of course you are told to take action. Examine with your pharmacist if you have questions about The simplest way to toss out medications. There may be drug choose-back again programs close to you. Customer Facts Use and Disclaimer
As with other opioids, codeine more info sulfate needs to be utilised with caution in aged or debilitated clients and people with extreme impairment of hepatic or renal functionality, hypothyrodism, Addison's disease, prostatic hypertrophy or urethral stricture [see Use in Distinct Populations].
The lowest powerful dose with the drug ought to be utilised. Concomitant usage of promethazine with other respiratory depressants need to be avoided.
Infants born to moms bodily dependent on opioids can even be bodily dependent and could exhibit respiratory issues and withdrawal signs or symptoms [see Use in Particular Populations, OVERDOSAGE].
MAOIs here markedly potentiate the motion of morphine sulfate, the key metabolite of codeine. Codeine shouldn't be Employed in sufferers taking MAOIs or in just fourteen days of halting these click here remedy.